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Effects of Clopidogrel Added to Aspirin in Patients with Recent Lacunar Stroke
NEJM 367:817-825, The SPS3 Investigators, 2012
See this aricle in Pubmed

Article Abstract
Among patients with recent lacunar strokes, the addition of clopidogrel to aspirin did not significantly reduce the risk of recurrent stroke and did significantly increase the risk of bleeding and death.
 
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aspirin
cerebrovascular accident,prevention of
cerebrovascular accident,recurrent
clopidogrel
complications
efficacy
hemorrhagic diathesis
lacunar infarction
mortality
platelet inhibiting drugs
platelet inhibiting drugs,combined
prevention of neurologic disorders
treatment of neurologic disorder

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